Detalhe da pesquisa
1.
Chromosomal Mcm2-7 distribution and the genome replication program in species from yeast to humans.
PLoS Genet
; 17(9): e1009714, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34473702
2.
Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats.
PLoS Genet
; 15(5): e1008138, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31083663
3.
The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion.
J Biol Chem
; 294(42): 15257-15270, 2019 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31431503
4.
5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts.
BMC Cancer
; 20(1): 1090, 2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33176741
5.
SIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences.
Proc Natl Acad Sci U S A
; 114(3): 552-557, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049846
6.
Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-ß superfamily as a regulator of XIST expression.
Proc Natl Acad Sci U S A
; 114(7): 1619-1624, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28143937
7.
Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies.
Molecules
; 25(3)2020 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31973227
8.
A high-throughput small molecule screen identifies synergism between DNA methylation and Aurora kinase pathways for X reactivation.
Proc Natl Acad Sci U S A
; 113(50): 14366-14371, 2016 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28182563
9.
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Nature
; 477(7365): 482-5, 2011 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21938067
10.
Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Nature
; 521(7552): E1-4, 2015 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25993969
11.
Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Nature
; 525(7570): 552, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26176914
12.
A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan.
PLoS Genet
; 9(3): e1003329, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23505383
13.
Inositol pyrophosphates modulate S phase progression after pheromone-induced arrest in Saccharomyces cerevisiae.
J Biol Chem
; 288(3): 1717-25, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23179856
14.
SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.
Blood
; 119(8): 1856-60, 2012 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22219225
15.
Genetic variation shapes protein networks mainly through non-transcriptional mechanisms.
PLoS Biol
; 9(9): e1001144, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21909241
16.
Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast.
PLoS Genet
; 7(8): e1002250, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21901113
17.
SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.
PLoS Genet
; 7(6): e1002135, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21698133
18.
Identification of 1600 replication origins in S. cerevisiae.
Elife
; 122024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38315095
19.
Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy.
bioRxiv
; 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38585982
20.
Donor bone marrow-derived macrophage engraftment into the central nervous system of patients following allogeneic transplantation.
Blood Adv
; 7(19): 5851-5859, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315172